Tempus
AI-enabled precision medicine for data-driven healthcare decisions.
Updated 12d ago
Has API
PricingFree
Free
Genomic Profiling
Clinical Trial Matching
Drug Target Discovery
GeneMANIA
4.9
Free Extremely high praise within the academic community for its ease of use and the depth of integrated data.
Advanced gene function prediction and association network integration for precision genomics.
Free pricingAPI availableUpdated 2026-03-17
Best fits
Gene function predictionRegulatory network reconstruction
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About GeneMANIA
GeneMANIA is a robust biological network integration and gene function prediction engine designed for high-throughput genomic data analysis. Developed by the University of Toronto, it utilizes a Gaussian Markov Random Field (GMRF) approach and a 'Guilt-by-Association' algorithm to integrate massive datasets—including protein-protein interactions, genetic interactions, co-expression patterns, and shared protein domains. By 2026, it remains a gold-standard tool in the systems biology community for its ability to weight disparate data sources based on their relevance to a specific query. The platform supports multiple model organisms and allows researchers to prioritize genes for functional assays, identify novel members of signaling pathways, and interpret complex transcriptomic results. Its architecture is optimized for both web-based exploration and deep integration with Cytoscape and R/Bioconductor environments, making it indispensable for identifying drug targets and understanding disease mechanisms in a multi-omic context.
Core Capabilities
GeneMANIA is a robust biological network integration and gene function prediction engine designed for high-throughput genomic data analysis.
