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Orchid Health

4.8

Paid

Highly praised by prospective parents for the peace of mind it provides and the depth of the data. Some users note the high out-of-pocket cost as a barrier, but value the integrated genetic counseling.

Advanced whole-genome embryo screening and genetic testing to conceive with confidence.

HealthTechPaid pricingAPI availableUpdated 2026-03-17

Best fits

Whole genome sequencing for embryosPreconception carrier screening

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Orchid Health interface

About Orchid Health

Orchid Health is a pioneering biotechnology company specializing in ultra-high-resolution genetic screening for prospective parents and embryos. Utilizing whole-genome sequencing (WGS), Orchid provides unprecedented visibility into the genetic health of embryos during the IVF process. While traditional Preimplantation Genetic Testing (PGT-A) only counts chromosomes, Orchid sequences over 3 billion base pairs to detect monogenic single-gene disorders, structural variations, de novo mutations, and complex polygenic risks for chronic diseases such as Type 1 Diabetes, Schizophrenia, and certain cancers. Designed for couples undergoing IVF or planning for pregnancy, Orchid's platform bridges the gap between advanced bioinformatics and accessible clinical care. The service includes rigorous couple carrier screening via simple saliva tests, secure data processing, and integrated tele-genetic counseling to help patients interpret their customized genomic reports. By offering a comprehensive preventative health roadmap before conception, Orchid empowers families to mitigate severe hereditary disease risks, improve the likelihood of successful embryo transfers, and invest in the long-term health of their future children.

Core Capabilities

Orchid Health is a pioneering biotechnology company specializing in ultra-high-resolution genetic screening for prospective parents and embryos.

Main Tasks

Use Cases

IVF Embryo Selection and Prioritization

Patients need to know which embryo has the highest chance of resulting in a healthy pregnancy and baby, beyond basic chromosomal counts.

VIEW EXECUTION STEPS

1.

IVF Clinic performs an embryo biopsy and cryopreserves the embryos.

2.

Biopsy cells are shipped to the Orchid clinical laboratory securely.

3.

DNA is amplified and whole genome sequencing is performed.

4.

Clinic and parents receive a comprehensive risk report to confidently select the most viable embryo for transfer.

Comprehensive Preconception Screening

Couples want to know their combined risk of passing down recessive genetic diseases before attempting to conceive.

VIEW EXECUTION STEPS

1.

Couple orders Orchid saliva test kits online or through their physician.

2.

Samples are collected at home and mailed back to the laboratory.

3.

Lab sequences both genomes comprehensively and checks for matching recessive mutations.

4.

Couple reviews the results via a telehealth session with an Orchid genetic counselor.

Mitigating Hereditary Cancer Risks

A patient with a strong family history of BRCA mutations wants to ensure their child does not inherit the high-risk gene.

VIEW EXECUTION STEPS

1.

Patient with BRCA family history undergoes an IVF cycle.

2.

Orchid screens the resulting embryos specifically for BRCA1/BRCA2 and other oncological pathogenic variants.

3.

Pathogenic variants are clearly flagged in the clinical report.

4.

Genetically healthy embryos without the mutation are prioritized for transfer.

Advanced Maternal Age Pregnancy Planning

Older prospective mothers face higher risks of chromosomal anomalies and spontaneous mutations causing miscarriage or severe developmental disorders.

VIEW EXECUTION STEPS

1.

Older parents initiate IVF and opt for Orchid's advanced embryo screening.

2.

Orchid performs ultra-high-resolution screening for both aneuploidy and sub-chromosomal structural variations.

3.

Microdeletions and duplications that standard PGT misses are identified.

4.

The most viable, chromosomally normal embryo is transferred, heavily reducing the risk of miscarriage.

Investigating Recurrent Pregnancy Loss

Couples experiencing multiple unexplained miscarriages need deep genetic insights to find viable embryos.

VIEW EXECUTION STEPS

1.

Couple opts for whole genome sequencing to investigate subtle genetic incompatibilities.

2.

Both partners' genomes are analyzed to detect complex translocations or structural variations.

3.

Embryos are screened at ultra-high resolution to ensure perfectly balanced chromosomal structures.

4.

A healthy pregnancy is achieved through precise, genetically informed selection.

Mitigating Psychiatric Disease Risk (e.g., Schizophrenia)

Families with a history of severe psychiatric disorders want to minimize the risk of their child developing the condition.

VIEW EXECUTION STEPS

1.

Couple undergoes IVF and selects Orchid for complex polygenic screening.

2.

Embryo DNA is sequenced to analyze thousands of variants associated with neurological development.

3.

Polygenic risk scores (PRS) for conditions like schizophrenia and bipolar disorder are calculated.

4.

Embryos demonstrating baseline or lower-than-average risk are prioritized for transfer.