Executes all deep learning training and inference directly within Google Colab notebooks, requiring only a web browser and a Google account. Users never need to install CUDA, PyTorch/TensorFlow, or manage GPU drivers on their own machines.
Provides a curated library of Jupyter notebooks, each dedicated to a specific bioimage analysis problem like Noise2Void denoising, StarDist segmentation, or CARE super-resolution. Each notebook is a complete, self-contained workflow.
Integrates IPython widgets (like sliders, dropdowns, and file uploaders) directly into the notebooks, allowing users to configure model training and data paths through a simple graphical interface without editing code.
Automatically generates and displays training curves (loss/accuracy), sample predictions, and quality control metrics during and after model training within the notebook.
Offers access to pre-trained models for common structures and modalities, and allows easy saving/loading of user-trained model weights for future use or sharing.
A cell biologist needs to count and measure the size/shape of thousands of nuclei in a high-throughput screen. Using the 'Cellpose' or 'StarDist' notebook in ZeroCostDL4Mic, they upload their multi-channel fluorescence images. The platform trains a model to accurately segment individual nuclei, even when they are touching or irregularly shaped. The output provides binary masks and quantitative data (counts, areas, intensities) ready for statistical analysis, replacing error-prone manual thresholding.
A researcher performing long-term live-cell imaging must use low laser power to avoid phototoxicity, resulting in noisy, low-signal-to-noise ratio videos. They use the 'Noise2Void' or 'DivNoising' notebook to train a self-supervised denoising model directly on their noisy data. The model learns to remove noise while preserving biological structures, yielding clearer videos for tracking cell movement or organelle dynamics without requiring paired clean/noisy data.
A lab without access to expensive super-resolution microscopes wants to enhance the resolution of their confocal images. They employ the 'CARE' (Content-Aware Image Restoration) notebook. By training a model on pairs of lower- and higher-resolution images (or using a cyclical approach), they can infer sub-diffraction limit details from standard microscopy data, enabling finer structural analysis of synapses or protein clusters at a fraction of the hardware cost.
A biophysicist studies the transport of vesicles inside neurons. They have time-lapse movies showing moving particles but need to track each particle's trajectory over hundreds of frames. Using the tracking notebooks, they segment particles in each frame and then link these detections across time. The tool outputs trajectories, velocities, and diffusion coefficients, automating a process that would be impossibly tedious to do manually for thousands of particles.
An instructor running a workshop or course on computational microscopy uses ZeroCostDL4Mic as the primary teaching tool. Students can immediately run cutting-edge algorithms on provided example datasets without any software installation. The interactive notebooks allow them to tweak parameters and see the effects in real-time, providing a hands-on understanding of how deep learning models work and how they are applied to real biological questions.
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15Five operates in the people analytics and employee experience space, where platforms aggregate HR and feedback data to give organizations insight into their workforce. These tools typically support engagement surveys, performance or goal tracking, and dashboards that help leaders interpret trends. They are intended to augment HR and management decisions, not to replace professional judgment or context. For specific information about 15Five's metrics, integrations, and privacy safeguards, you should refer to the vendor resources published at https://www.15five.com.
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